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CyFlow™ CD4 APC-Cy7

CyFlow™ CD4 APC-Cy7
Alternative Name: Leu3a, T4
Antigen: CD4
Application: Flow cytometry
Clonality: monoclonal
Clone: MEM-241
Emission Maximum: 780 nm
Excitation Maximum: 650 nm, 750 nm
Field of Interest: Immunophenotyping
Format/Fluorochrome: APC-Cy7
Isotype: IgG1
Laser: Red
Regulatory Status: CE IVD
Source Species: Mouse
Target Species: Human
Product number: CV992220

CE IVD

HLDA Workshop HCDM (HLDA VIII)—WS Code M241 Concentration Unit µg/mL Concentration... more
CyFlow™ CD4 APC-Cy7

HLDA WorkshopHCDM (HLDA VIII)—WS Code M241
Concentration Unitµg/mL
Concentration20
Quantity100 tests
Volume1.0 mL
Immunogen2 N-terminal domains of human CD4 fused to human IgG1 Fc
Background InformationCD4 (T4, Leu3a) is a 55 kDa single-chain transmembrane glycoprotein expressed on a subset of T lymphocytes (''helper'' T-cells) and also on monocytes, tissue macrophages and granulocytes. In extracellular region there are 4 immunoglobulin-like domains (1 Ig-like V-type and 3 Ig-like C2-type). Transmembrane region forms 25 aa, cytoplasmic tail consists of 38 aa. Domains 1, 2 and 4 are stabilized by disulfide bonds. The intracellular domain of CD4 is associated with p56Lck, a Src-like protein tyrosine kinase.
Antigen DistributionCD4 (T4, Leu3a) is a 55 kDa single-chain transmebrane glycoprotein expressed on a subset of T lymphocytes (''helper'' T-cells) and also on monocytes, tissue macrophages and granulocytes. In extracellular region there are 4 immunoglobulin-like domains (1 Ig-like V-type and 3 Ig-like C2-type). Transmembrane region forms 25 aa, cytoplasmic tail consists of 38 aa. Domains 1, 2 and 4 are stabilized by disulfide bonds. The intracellular domain of CD4 is associated with p56Lck, a Src-like protein tyrosine kinase.
UsageCE IVD usage Placeholder
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Specific References

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