CyFlow™ CD11c APC
| Alternative Name: | p150 |
| Antigen: | CD11c |
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Clone: | BU15 |
| Emission Maximum: | 660 nm |
| Excitation Maximum: | 650 nm |
| Field of Interest: | Immunophenotyping |
| Format/Fluorochrome: | APC |
| Isotype: | IgG1 |
| Laser: | Red |
| Regulatory Status: | CE IVD |
| Source Species: | Mouse |
| Target Species: | Human |
| Product number: | BT732392 |
CE IVD
| HLDA Workshop | HLDA III—WS Code M 256 HLDA V—WS Code AS S143 HLDA VI—WS Code AS Ref.6 |
| Concentration Unit | µg/mL |
| Concentration | 25 |
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Dendritic cells of synovial fluid |
| Background Information | CD11c (αX integrin subunit) forms complex with CD18 (β2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other β2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b. |
| Antigen Distribution | CD11c (αX integrin subunit) is a 150 kDa integrin expressed mainly on tissue macrophages and dendritic cells. |
| Usage | CE IVD usage Placeholder |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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