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CyFlow™ CD24 APC

CyFlow™ CD24 APC
Alternative Name: BA 1 , HAS
Antigen: CD24
Application: Flow cytometry
Clonality: monoclonal
Clone: SN3
Emission Maximum: 660 nm
Excitation Maximum: 650 nm
Field of Interest: Immunophenotyping
Format/Fluorochrome: APC
Isotype: IgG1
Laser: Red
Regulatory Status: CE IVD
Source Species: Mouse
Target Species: Human
Product number: CS363236

CE IVD

HLDA Workshop HLDA IV—WS Code B 136 HLDA V—WS Code B CD24.7 Concentration Unit µg/mL... more
CyFlow™ CD24 APC

HLDA WorkshopHLDA IV—WS Code B 136 HLDA V—WS Code B CD24.7
Concentration Unitµg/mL
Concentration120
Quantity100 tests
Volume1.0 mL
ImmunogenGlycoproteins purified from human NALM-1 cell line
Background InformationCD24 (BA 1, HSA) is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation.
Antigen DistributionCD24 (BA 1, HSA) is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation.
UsageCE IVD usage Placeholder
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Specific References

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