CyFlow™ CD61 FITC
| Alternative Name: | GPIIIa |
| Antigen: | CD61 |
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Clone: | VIPL2 |
| Emission Maximum: | 518 nm |
| Excitation Maximum: | 490 to 495 nm |
| Field of Interest: | Immunophenotyping |
| Format/Fluorochrome: | FITC |
| Isotype: | IgG1 |
| Laser: | Blue |
| Regulatory Status: | CE IVD |
| Source Species: | Mouse |
| Target Species: | Human |
| Product number: | AR902616 |
CE IVD
| HLDA Workshop | HLDA V—WS Code 5T-124 |
| Concentration Unit | µg/mL |
| Concentration | 50 |
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Not available |
| Background Information | CD61 (β3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells. |
| Antigen Distribution | CD61 (GPIIIa) is a 90-110 kDa transmembrane glycoprotein (integrin family) expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leukocytes and smooth muscle cells. CD61 associates with CD41 or CD51 molecules to form heterodimeric adhesion receptors. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex is involved in modulating migration and survival of angiogenic endothelial cells. |
| Usage | CE IVD usage Placeholder |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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