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CyFlow™ CD123 PerCP-Cy5.5

CyFlow™ CD123 PerCP-Cy5.5
Alternative Name: IL-3Ra , IL3R
Antigen: CD123
Application: Flow cytometry
Clonality: monoclonal
Clone: 6H6
Emission Maximum: 695 nm
Excitation Maximum: 482 nm
Field of Interest: Immunophenotyping, Signaling
Format/Fluorochrome: PerCP-Cy5.5
Isotype: IgG1
Laser: Blue , Green
Regulatory Status: CE IVD
Source Species: Mouse
Target Species: Human
Product number: AX349290

CE IVD

Concentration Unit µg/mL Concentration 50 Quantity 100 tests Volume 1.0 mL... more
CyFlow™ CD123 PerCP-Cy5.5

Concentration Unitµg/mL
Concentration50
Quantity100 tests
Volume1.0 mL
ImmunogenIL3 receptor α chain expressed on the surface of transiently transfected COS cells
Background InformationCD123 is the α chain of interleukin 3 receptor (IL-3R α). This subunit heterodimerizes with the interleukin 3 receptor β chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the β subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
Antigen DistributionCD123 (IL-3Ra, IL3R) is the α chain of interleukin 3 receptor. This subunit heterodimerizes with the interleukin 3 receptor β chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the β subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signalling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
UsageCE IVD usage Placeholder
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Specific References

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